SCHEMBL31455720

SCHEMBL31455720

COC(=O)Cc1cccc(C(=O)O)c1F

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 9/20 0.46
CLCN2 P51788 1/20 0.42
KDM4E B2RXH2 2/20 0.42
KAT6A Q92794 1/20 0.41
MAPK1 P28482 1/20 0.40
ALB P02768 1/20 0.40
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
FABP4 P15090 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3916488 0.83 FOLH1 (0.50) CLCN2KDM4EMAPK1HPGDHSD17B10
SCHEMBL506923 0.81 SMN1; SMN2 (0.46) KDM4EMAPK1
SCHEMBL2972991 0.80 MEP1B (0.48) KDM4EHPGD
SCHEMBL4238088 0.79 KAT6A (0.54) MRGPRX4CLCN2KDM4EKAT6AALB
SCHEMBL27984139 0.79 KDM4E (0.43) KDM4EMAPK1
SCHEMBL31284578 0.79 KDM4E (0.43) KDM4EMAPK1
SCHEMBL18261999 0.79 KDM4E (0.43) KDM4E
SCHEMBL27714282 0.79 SMN1; SMN2 (0.50) KDM4EMAPK1HPGD
SCHEMBL30701130 0.77 ALDH1A1 (0.48) MRGPRX4CLCN2KAT6AMAPK1ALB
SCHEMBL31645683 0.76 P2RX7 (0.47) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059562-A1 SUBSTITUTED AMINOPYRIDINE COMPOUNDS AND METHODS OF TREATING DISEASE USING SAME ATAVISTIK BIO, INC. (US) 2025-03-20 WO disclosed