Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.46 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.44 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25293555 | 0.99 | KMT2A (0.54) | KMT2AHPGDMEN1TSHRHRH3 | |
| SCHEMBL25253834 | 0.85 | LMNA (0.47) | HRH3STSMMP1KCNA1KCNAB1 | |
| SCHEMBL29178274 | 0.80 | CA12 (0.53) | KMT2AMAPTLMNA | |
| Tolpyrramide SCHEMBL667821 | 0.80 | KMT2A (0.64) | KMT2AHPGDMEN1KDM4EKCNA1 | |
| SCHEMBL25256003 | 0.79 | STS (0.64) | KMT2AMEN1TSHRKCNH2STS | |
| SCHEMBL31456338 | 0.79 | ALDH1A1 (0.67) | KMT2AHPGDKDM4EKCNA1KCNAB1 | |
| SCHEMBL14794998 | 0.78 | POLB (0.54) | KMT2AHPGDLMNAPOLB | |
| SCHEMBL24713395 | 0.77 | MMP1 (0.57) | KMT2AMEN1HRH3MMP1MAPT | |
| SCHEMBL12459304 | 0.77 | GAA (0.58) | KMT2AMEN1KDM4ELMNAPOLB | |
| SCHEMBL1951647 | 0.76 | MMP1 (0.55) | KMT2AMEN1MMP1MAPTALKBH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250049736-A1 | SULFONAMIDE DERIVATIVES AND THEIR USE AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | THE US SECRETARY DEPARTMENT OF HEALTH (US) | 2025-02-13 | — | — | US | disclosed |
| EP-4448491-A2 | N-((ADAMANTAN-1-YL)CARBAMOYL)-BENZENESULFONAMIDE DERIVATIVES AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS FOR THE TREATMENT OF HYPERTENSION | The United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114366-A2 | SULFONAMIDE DERIVATIVES AND THEIR USE AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250049736-A1 | SULFONAMIDE DERIVATIVES AND THEIR USE AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | EPHX1, FAAH, ECE1 | KMT2A 2424/4885HPGD 139/4885MEN1 3974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.