Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | CALCA | P06881 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27374784 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNAHPGDADORA2AADORA2B | |
| SCHEMBL27376320 | 0.88 | ADORA2A (0.43) | ALDH1A1LMNAHPGDADORA2AADORA2B | |
| Hydrochloric Acid SCHEMBL31456967 | 0.87 | ADORA2A (0.42) | ALDH1A1LMNAHPGDADORA2AADORA2B | |
| SCHEMBL27376324 | 0.87 | CALCA (0.42) | ALDH1A1LMNAHPGDADORA2AADORA2B | |
| SCHEMBL31456925 | 0.87 | CALCA (0.42) | ALDH1A1LMNAHPGDADORA2AADORA2B | |
| SCHEMBL30751370 | 0.86 | CALCA (0.40) | ADORA2AADORA2BCALCAADORA1DYRK1A | |
| SCHEMBL27374797 | 0.86 | CALCA (0.40) | ADORA2AADORA2BCALCAADORA1DYRK1A | |
| SCHEMBL27374812 | 0.86 | ADORA1 (0.41) | ADORA2AADORA2BCALCAADORA1BTK | |
| SCHEMBL30751269 | 0.86 | ADORA1 (0.41) | ADORA2AADORA2BCALCAADORA1BTK | |
| SCHEMBL21174216 | 0.84 | ADORA1 (0.41) | ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | claimed |
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |