Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCA | P06881 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27376324 | 1.00 | CALCA (0.42) | CALCAALDH1A1LMNAHPGDTP53 | |
| SCHEMBL31456923 | 0.87 | ALDH1A1 (0.46) | CALCAALDH1A1LMNAHPGDADORA2A | |
| SCHEMBL27374784 | 0.87 | ALDH1A1 (0.46) | CALCAALDH1A1LMNAHPGDADORA2A | |
| SCHEMBL30751273 | 0.85 | GRIN2B (0.41) | CALCAALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL27376309 | 0.85 | CALCA (0.40) | CALCAALDH1A1LMNAHPGDTP53 | |
| SCHEMBL31457053 | 0.85 | GRIN2B (0.41) | CALCAALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL30751066 | 0.83 | MET (0.47) | CALCADYRK1ASMN1; SMN2 | |
| SCHEMBL30751053 | 0.83 | MET (0.47) | CALCADYRK1ASMN1; SMN2 | |
| SCHEMBL27376205 | 0.83 | MET (0.47) | CALCADYRK1ASMN1; SMN2 | |
| SCHEMBL27376283 | 0.83 | MET (0.47) | CALCADYRK1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | claimed |
| CN-119654324-A | Novel compounds as hypoxia inducible factor 1 (HIF-1) inhibitors or Vascular Endothelial Growth Factor (VEGF) inhibitors and pharmaceutical compositions comprising the same | 株式会社次代生物科学 | 2025-03-18 | — | — | CN | disclosed |