Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HCN1 | O60741 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23623288 | 1.00 | KMT2A (0.47) | KMT2AMEN1L3MBTL1HCN1OPRM1 | |
| SCHEMBL24177588 | 0.88 | KMT2A (0.46) | KMT2AMEN1L3MBTL1USP2MAPT | |
| SCHEMBL23623286 | 0.86 | KMT2A (0.47) | KMT2AMEN1L3MBTL1USP2MAPT | |
| SCHEMBL23611754 | 0.84 | KMT2A (0.48) | KMT2AMEN1L3MBTL1USP2MAPT | |
| SCHEMBL23623487 | 0.83 | KCNK3 (0.44) | HCN1OPRM1KCNK3KCNK9RXFP1 | |
| SCHEMBL23623645 | 0.83 | HCN1 (0.43) | HCN1OPRM1KCNK3KCNK9RXFP1 | |
| SCHEMBL23623486 | 0.83 | HCN1 (0.41) | HCN1OPRM1KCNK3KCNK9RXFP1 | |
| SCHEMBL24177586 | 0.82 | KMT2A (0.46) | KMT2AMEN1L3MBTL1USP2MAPT | |
| SCHEMBL23623491 | 0.82 | OPRM1 (0.42) | HCN1OPRM1KCNK3KCNK9RXFP1 | |
| SCHEMBL23623344 | 0.82 | OPRM1 (0.42) | KMT2AMEN1HCN1OPRM1KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260028355-A1 | PROTEOLYSIS TARGETING CHIMERA (PROTAC) COMPOSITIONS USING UBIQUITIN CONJUGATING ENZYME LIGANDS | BERG, KARA ANN | 2026-01-29 | — | — | US | disclosed |
| US-20250262309-A1 | PROTEOLYSIS TARGETING CHIMERA (PROTAC) COMPOSITIONS USING UBIQUITIN CONJUGATING ENZYME LIGANDS | BERG, KARA ANN | 2025-08-21 | — | — | US | disclosed |
| CN-119546341-A | Proteolytic targeting chimeric (PROTAC) compositions using ubiquitin conjugated enzyme ligands | 布普格生物制药公司 | 2025-02-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250262309-A1 | PROTEOLYSIS TARGETING CHIMERA (PROTAC) COMPOSITIONS USING UBIQUITIN CONJUGATING ENZYME LIGANDS | UBE3C, UBE3A, MDM2 | KMT2A 659/4885MEN1 4190/4885L3MBTL1 1422/4885 |
| US-20260028355-A1 | PROTEOLYSIS TARGETING CHIMERA (PROTAC) COMPOSITIONS USING UBIQUITIN CONJUGATING ENZYME LIGANDS | UBE2T, UBE3C, UBE2E1 | KMT2A 724/4885MEN1 3261/4885L3MBTL1 960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.