Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28302605 | 0.84 | TAAR1 (0.44) | HSPA5MPOCYP2D6TSHRHIF1A | |
| SCHEMBL5816301 | 0.79 | C1R (0.38) | CYP2D6TAAR1IDO1CYP1A2 | |
| SCHEMBL7822927 | 0.79 | TAAR1 (0.41) | TSHRTAAR1CA12CA2IDO1 | |
| SCHEMBL9057228 | 0.79 | AR (0.43) | IDO1 | |
| SCHEMBL17002520 | 0.77 | HTR1A (0.36) | HSPA5MPOCYP2D6TSHRHIF1A | |
| SCHEMBL12017477 | 0.76 | AR (0.46) | GAAMAPT | |
| SCHEMBL1249225 | 0.76 | ADRA2A (0.53) | CYP2D6TAAR1CYP1A2LMNAGAA | |
| SCHEMBL12017482 | 0.76 | SLC6A4 (0.41) | MAPTPKM | |
| SCHEMBL2660074 | 0.76 | ALDH1A1 (0.37) | TSHRMAPT | |
| SCHEMBL3149895 | 0.75 | AR (0.47) | TSHRTAAR1IDO1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081692-A1 | Novel 1-Benzyl-4-Piperidinamines that are Useful in the Treatment of COPD and Asthma | ASTRAZENECA AB (SE) | 2010-04-01 | — | — | US | disclosed |
| CN-101351448-A | Novel 1-benzyl-4-piperidinamines for the treatment of COPD and asthma | ASTRAZENECA AB (SE) | 2009-01-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081692-A1 | Novel 1-Benzyl-4-Piperidinamines that are Useful in the Treatment of COPD and Asthma | CCR1, CCR4, CCR10 | HSPA5 2011/4885KEAP1 152/4885MPO 999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.