SCHEMBL314576

SCHEMBL314576

CCCCCCCCCCCCCCCCOCC(O)C(=O)[N]CCO

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.50
HTT P42858 2/20 0.45
MEN1 O00255 1/20 0.43
THRB P10828 1/20 0.43
KMT2A Q03164 1/20 0.43
MAPT P10636 1/20 0.43
LPAR5 Q9H1C0 1/20 0.43
PLA2G2C Q5R387 4/20 0.43
SPHK1 Q9NYA1 1/20 0.42
CES2 O00748 2/20 0.41
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
LPAR1 Q92633 2/20 0.39
LPAR3 Q9UBY5 2/20 0.39
NAAA Q02083 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21273820 0.74 HTT (0.58) USP2HTTLPAR5PLA2G2CSPHK1
SCHEMBL11348967 0.73 GPR84 (0.53) USP2HTTLPAR5PLA2G2CSPHK1
SCHEMBL24339810 0.72 USP2 (0.53) USP2HTTLPAR5PLA2G2CSPHK1
SCHEMBL29169783 0.72 SPHK1 (0.69) USP2HTTMEN1THRBKMT2A
SCHEMBL7757196 0.70 SPHK1 (0.66) USP2HTTMEN1THRBKMT2A
SCHEMBL5157100 0.70 USP2 (0.75) USP2HTTMEN1THRBKMT2A
Ethylene Glycol SCHEMBL5711855 0.70 USP2 (0.63) USP2HTTMEN1THRBKMT2A
SCHEMBL16187998 0.70 USP2 (0.69) USP2HTTMEN1THRBKMT2A
SCHEMBL16187997 0.70 USP2 (0.69) USP2HTTMEN1THRBKMT2A
SCHEMBL28128054 0.70 USP2 (0.69) USP2HTTMEN1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 370 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3134065-B1 COMPOSITION IN THE FORM OF NANO- OR MICRO- EMULSION OREAL (FR) 2021-04-21 EP claimed
CN-106456516-B Composition in form of nanoemulsion or microemulsion 莱雅公司 2020-09-29 CN claimed
US-10561587-B2 Composition in the form of nano- or micro-emulsion L'OREAL (FR) 2020-02-18 US claimed
US-20170156998-A1 COMPOSITION IN THE FORM OF NANO- OR MICRO-EMULSION L'OREAL (FR) 2017-06-08 US claimed
EP-3134065-A1 COMPOSITION IN THE FORM OF NANO- OR MICRO- EMULSION L'OREAL (FR) 2017-03-01 EP claimed
WO-2015152420-A1 COMPOSITION IN THE FORM OF NANO- OR MICRO- EMULSION L'OREAL (FR) 2015-10-08 WO claimed
EP-1842528-B1 Cosmetic composition comprising at least one hydroxy acid, at least one mono- or disaccharide and at least one ceramide, and process for the preparation thereof ORÉAL L (FR) 2015-04-15 EP claimed
US-20150044154-A1 COMPOSITION FOR THE TREATMENT OF KERATINOUS FIBERS COMPRISING AT LEAST ONE FIXING POLYMER AND AT LEAST ONE COMPOUND OF THE CERAMIDE TYPE AND METHODS FOR USING THE COMPOSITION OREAL (FR) 2015-02-12 US claimed
EP-0774248-B2 Keratinous fiber treating composition containing at least a binding polymer and at least a ceramide-type compound and methods OREAL (FR) 2014-03-12 EP claimed
US-20110286940-A1 COMPOSITION FOR THE TREATMENT OF KERATINOUS FIBERS COMPRISING AT LEAST ONE FIXING POLYMER AND AT LEAST ONE COMPOUND OF THE CERAMIDE TYPE AND METHODS FOR USING THE COMPOSITION L'OREAL S.A. (FR) 2011-11-24 US claimed
EP-0774248-B1 Keratinous fiber treating composition containing at least a binding polymer and at least a ceramide-type compound and methods OREAL (FR) 1999-02-10 EP claimed
EP-0862405-A1 COMPOSITION FOR TREATING KERATINOUS MATERIAL, INCLUDING AT LEAST ONE SILICONE-GRAFTED POLYMER AND AT LEAST ONE FATTY-CHAIN AMIDE, AND USES THEREOF L'OREAL (FR) 1998-09-09 EP claimed
EP-0852134-A1 Use of a composition containing a ceramide and a sulphonic UV filter L'OREAL (FR) 1998-07-08 EP claimed
EP-0704200-B1 Cosmetic compositions containing a lipid ceramide-type compound and a peptide with a fatty chain OREAL (FR) 1997-07-23 EP claimed
EP-0774248-A1 Keratinous fiber treating composition containing at least a binding polymer and at least a ceramide-type compound and methods L'OREAL (FR) 1997-05-21 EP claimed
WO-1997015274-A1 KERATIN FIBRE TREATMENT COMPOSITION INCLUDING AT LEAST ONE SETTING POLYMER AND AT LEAST ONE CERAMIDE-TYPE COMPOUND, AND METHODS L'OREAL (FR) 1997-05-01 WO claimed
WO-1997012587-A1 COMPOSITION FOR TREATING KERATINOUS MATERIAL, INCLUDING AT LEAST ONE SILICONE-GRAFTED POLYMER AND AT LEAST ONE FATTY-CHAIN AMIDE, AND USES THEREOF L'OREAL (FR) 1997-04-10 WO claimed
EP-0699430-B1 Method of hair treatment using amides containing fatty chains and steam OREAL (FR) 1996-10-02 EP claimed
EP-0704200-A1 Cosmetic compositions containing a lipid ceramide-type compound and a peptide with a fatty chain L'OREAL (FR) 1996-04-03 EP claimed
EP-0699430-A1 Method of hair treatment using amides containing fatty chains and steam L'OREAL (FR) 1996-03-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10561587-B2 Composition in the form of nano- or micro-emulsion SGMS2, LIPA, CERS2 USP2 3538/4885HTT 1208/4885MEN1 834/4885
US-20110286940-A1 COMPOSITION FOR THE TREATMENT OF KERATINOUS FIBERS COMPRISING AT LEAST ONE FIXING POLYMER AND AT LEAST ONE COMPOUND OF THE CERAMIDE TYPE AND METHODS FOR USING THE COMPOSITION CERT1, KRT18, SGMS1 USP2 3692/4885HTT 4073/4885MEN1 1401/4885
US-20150044154-A1 COMPOSITION FOR THE TREATMENT OF KERATINOUS FIBERS COMPRISING AT LEAST ONE FIXING POLYMER AND AT LEAST ONE COMPOUND OF THE CERAMIDE TYPE AND METHODS FOR USING THE COMPOSITION CERT1, KRT18, SGMS1 USP2 3692/4885HTT 4073/4885MEN1 1401/4885
US-20170156998-A1 COMPOSITION IN THE FORM OF NANO- OR MICRO-EMULSION SGMS2, LIPA, CERS2 USP2 3538/4885HTT 1208/4885MEN1 834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.