SCHEMBL5157100

SCHEMBL5157100

CCCCCCCCCCCCOCC(O)COCCO

nearest known ligand 0.75

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.75
HTT P42858 2/20 0.67
MEN1 O00255 1/20 0.67
THRB P10828 1/20 0.67
KMT2A Q03164 1/20 0.67
MAPT P10636 1/20 0.67
LPAR5 Q9H1C0 4/20 0.62
SPHK1 Q9NYA1 1/20 0.56
TSHR P16473 1/20 0.56
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C19 P33261 1/20 0.49
PLA2G2C Q5R387 2/20 0.48
LPAR1 Q92633 6/20 0.45
LPAR3 Q9UBY5 6/20 0.45
LPAR2 Q9HBW0 4/20 0.45
LPAR6 P43657 3/20 0.45
LPAR4 Q99677 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5155511 0.96 HTT (0.74) USP2HTTMEN1THRBKMT2A
SCHEMBL5154249 0.96 HTT (0.74) USP2HTTMEN1THRBKMT2A
SCHEMBL18681856 0.96 HTT (0.74) USP2HTTMEN1THRBKMT2A
SCHEMBL8900634 0.96 HTT (0.74) USP2HTTMEN1THRBKMT2A
SCHEMBL10711302 0.92 TSHR (0.67) USP2HTTMEN1THRBKMT2A
SCHEMBL10605202 0.92 USP2 (0.80) USP2HTTMEN1THRBKMT2A
SCHEMBL251104 0.92 USP2 (0.80) USP2HTTMEN1THRBKMT2A
SCHEMBL8527626 0.92 USP2 (0.80) USP2HTTMEN1THRBKMT2A
SCHEMBL2853658 0.92 USP2 (0.80) USP2HTTMEN1THRBKMT2A
SCHEMBL9117095 0.92 USP2 (0.80) USP2HTTMEN1THRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0660696-B2 LIPSTICKS PROCTER & GAMBLE (US) 2007-01-10 EP disclosed
EP-0950392-B1 Non-sweating lipsticks PROCTER & GAMBLE (US) 2004-12-29 EP disclosed
US-20020058051-A1 SKIN CARE COMPOSITIONS NAWAZ ZAHID (GB) 2002-05-16 US disclosed
US-6325995-B1 Lipsticks compositions containing association structures THE PROCTER & GAMBLE COMPANY 2001-12-04 US disclosed
EP-0725620-B1 NON-SWEATING LIPSTICKS PROCTER & GAMBLE (US) 2001-03-14 EP disclosed
US-6013269-A OIL-IN-WATER EMULSION COMPRISING VOLATILE SILICONE OIL AND/OR VOLATILE HYDROCARBON OIL, NON-VOLATILE OIL, PIGMENT AND ORGANIC AMPHIPHILIC MATERIAL CAPABLE OF FORMING SMECTIC LYOTROPIC LIQUID CRYSTALS IN PRODUCT OR ON THE SKIN THE PROCTER & GAMBLE COMPANY (US) 2000-01-11 US disclosed
EP-0950392-A1 Non-sweating lipsticks THE PROCTER & GAMBLE COMPANY (US) 1999-10-20 EP disclosed
US-5843407-A Non-sweating lipsticks THE PROCTER & GAMBLE COMPANY (US) 1998-12-01 US disclosed
US-5688831-A LIQUID CRYSTALS THE PROCTER & GAMBLE COMPANY (US) 1997-11-18 US disclosed
EP-0660696-B1 LIPSTICKS PROCTER & GAMBLE (US) 1997-01-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058051-A1 SKIN CARE COMPOSITIONS CUTA, KRT18, POLR1C USP2 2427/4885HTT 1593/4885MEN1 4564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.