Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.69 |
| ▸ | EHMT2 | Q96KQ7 | 16/20 | 0.63 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20745564 | 1.00 | ACHE (0.69) | ACHEEHMT2APPBCHETP53 | |
| SCHEMBL20745971 | 0.97 | ACHE (0.74) | ACHEEHMT2APPBCHETP53 | |
| SCHEMBL20756932 | 0.95 | ACHE (0.72) | ACHEEHMT2APPBCHETP53 | |
| SCHEMBL25489634 | 0.91 | ACHE (0.58) | ACHEEHMT2APPBCHETP53 | |
| SCHEMBL20746217 | 0.91 | EHMT2 (0.59) | ACHEEHMT2APPBCHETP53 | |
| SCHEMBL30063960 | 0.90 | ACHE (0.57) | ACHEEHMT2APPBCHETP53 | |
| SCHEMBL25489623 | 0.90 | ACHE (0.57) | ACHEEHMT2APPBCHETP53 | |
| SCHEMBL20756358 | 0.90 | EHMT2 (0.57) | ACHEEHMT2APPBCHETP53 | |
| SCHEMBL20745998 | 0.90 | ACHE (0.57) | ACHEEHMT2APPBCHETP53 | |
| SCHEMBL20745712 | 0.89 | ACHE (0.56) | ACHEEHMT2APPBCHETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668863-B1 | TRICYCLIC COMPOUNDS AS HISTONE METHYL-TRANSFERASE INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2025-03-19 | — | — | EP | disclosed |