Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.31 |
| ▸ | TTK | P33981 | 2/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31458696 | 0.86 | MAPK1 (0.33) | MAPK1LCKMAPK14JAK2PDE5A | |
| SCHEMBL31458730 | 0.84 | JAK2 (0.32) | JAK2KLKB1 | |
| SCHEMBL31458672 | 0.79 | NUDT1 (0.37) | JAK2 | |
| SCHEMBL31458577 | 0.73 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL25227147 | 0.68 | CD274 (0.39) | GRM2MAPK1LCKMAPK14PIM1 | |
| SCHEMBL31458746 | 0.67 | PDE1B (0.36) | MAPK1PIM1PSEN1PSEN2APH1B | |
| SCHEMBL31458608 | 0.66 | DGAT1 (0.31) | — | |
| SCHEMBL22247309 | 0.64 | MAOB (0.41) | — | |
| SCHEMBL22252741 | 0.63 | MAOB (0.37) | GRM2MAPK1PIM1JAK2 | |
| SCHEMBL31343456 | 0.63 | MAOB (0.37) | GRM2MAPK1PIM1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096061-A1 | CDK2 INHIBITORS AND USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |