SCHEMBL31458849

SCHEMBL31458849

CC1(NCC(O)c2cc3c(c(C(F)(F)F)c2)CN(C(=O)OC(C)(C)C)C3=O)CCC1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CBLB Q13191 11/20 0.36
CBLC Q9ULV8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31458941 0.84 CBLB (0.39) CBLB
SCHEMBL31458916 0.84 CBLB (0.48) CBLBCBLC
SCHEMBL31458984 0.80 CBLB (0.43) CBLB
SCHEMBL31459078 0.72 CBLB (0.36) CBLBCBLC
SCHEMBL31458950 0.71 HTR2A (0.37) CBLB
SCHEMBL31269996 0.66 GPR119 (0.47)
SCHEMBL32686321 0.64 CBLB (0.34) CBLB
SCHEMBL32686288 0.64 CBLB (0.34) CBLB
SCHEMBL27872576 0.62 CTSK (0.40)
SCHEMBL21211720 0.60 CBLB (0.48) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025067227-A1 PREPARATION METHOD FOR CBL-B REGULATOR, AND USE 浙江华海药业股份有限公司 2025-04-03 WO disclosed