Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 0.75 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | FHIT | P49789 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31459922 | 0.84 | MAPT (0.73) | MAPTMEN1KMT2AGAAALOX15 | |
| SCHEMBL31459864 | 0.80 | KMT2A (1.00) | MAPTMEN1KMT2AGAAALOX15 | |
| SCHEMBL15172955 | 0.80 | KMT2A (1.00) | MAPTMEN1KMT2AGAAALOX15 | |
| SCHEMBL3984848 | 0.80 | MAPT (0.67) | MAPTMEN1KMT2AGAAALOX15 | |
| SCHEMBL2925906 | 0.78 | TSHR (0.67) | MAPTMEN1KMT2AGAAALOX15 | |
| SCHEMBL3990578 | 0.78 | MAPT (0.64) | MAPTMEN1KMT2AGAAALOX15 | |
| SCHEMBL16521093 | 0.78 | MAPT (0.78) | MAPTMEN1KMT2AGAAALOX15 | |
| SCHEMBL15184999 | 0.78 | MAPT (0.78) | MAPTMEN1KMT2AGAAALOX15 | |
| SCHEMBL2308619 | 0.75 | MAPT (0.60) | MAPTMEN1KMT2AGAAALOX15 | |
| SCHEMBL24683238 | 0.73 | MAPT (0.57) | MAPTMEN1KMT2AGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250154163-A1 | Pyrimidinone-Containing 17-Beta-Hydroxysteroid Dehydrogenase Type 13 Inhibitors | ENANTA PHARMACEUTICALS, INC. | 2025-05-15 | — | — | US | disclosed |
| WO-2025090868-A1 | PYRIMIDINONE-CONTAINING 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2025-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250154163-A1 | Pyrimidinone-Containing 17-Beta-Hydroxysteroid Dehydrogenase Type 13 Inhibitors | HSD17B13, HSD17B1, HSD11B1 | MAPT 3628/4885MEN1 1840/4885KMT2A 3204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.