SCHEMBL3146069

SCHEMBL3146069

Nc1ccc(Oc2ccc(C(F)(F)C(F)(F)C(F)F)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
MAPT P10636 5/20 0.52
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
MAPK1 P28482 2/20 0.52
HPGD P15428 1/20 0.52
TDP1 Q9NUW8 2/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
MAOA P21397 2/20 0.44
MAOB P27338 3/20 0.42
TEAD4 Q15561 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
MITF O75030 1/20 0.41
GAA P10253 1/20 0.41
GFER P55789 1/20 0.41
NLRP1 Q9C000 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3146868 0.89 KIF11 (0.46) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL3137387 0.84 MAOB (0.53) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL8541418 0.83 NR4A1 (0.53) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL28511043 0.83 KIF11 (0.57) ALDH1A1MAPTNPC1RAB9AHPGD
SCHEMBL4854970 0.81 ALDH1A1 (0.41) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL9578149 0.81 ALDH1A1 (0.59) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL4810839 0.81 ALDH1A1 (0.59) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL22407382 0.81 L3MBTL1 (0.42) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL28390798 0.81 PDE7A (0.43) ALDH1A1MAPTNPC1RAB9AMAPK1
SCHEMBL4847389 0.80 ALDH1A1 (0.36) ALDH1A1MAPTNPC1RAB9AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116970169-B Amine compound modified maleimide prepolymer, resin composition and application thereof 苏州生益科技有限公司 2024-06-28 CN claimed
CN-117757072-A Modified maleimide prepolymer, resin composition and application thereof 苏州生益科技有限公司 2024-03-26 CN claimed
CN-117736579-A Preparation method and application of resin composition 常熟生益科技有限公司 2024-03-22 CN claimed
CN-116970169-A Amine compound modified maleimide prepolymer, resin composition and application thereof 苏州生益科技有限公司 2023-10-31 CN claimed
CN-115873251-A Modified maleimide prepolymer, preparation method thereof and resin composition 苏州生益科技有限公司 2023-03-31 CN claimed
CN-114605776-A Modified epoxy resin and preparation method thereof 中国航空制造技术研究院 2022-06-10 CN claimed
US-10246556-B2 Polyimide polymer and polyimide film TAIFLEX SCIENTIFIC CO., LTD. (TW) 2019-04-02 US claimed
US-20180371170-A1 POLYIMIDE POLYMER AND POLYIMIDE FILM TAIFLEX SCIENTIFIC CO., LTD. (TW) 2018-12-27 US claimed
CN-116970169-B Amine compound modified maleimide prepolymer, resin composition and application thereof 苏州生益科技有限公司 2024-06-28 CN disclosed
CN-118185310-A Resin composition and application thereof 常熟生益科技有限公司 2024-06-14 CN disclosed
CN-117777722-A Maleimide resin composition and application thereof 苏州生益科技有限公司 2024-03-29 CN disclosed
CN-117757072-A Modified maleimide prepolymer, resin composition and application thereof 苏州生益科技有限公司 2024-03-26 CN disclosed
CN-117736579-A Preparation method and application of resin composition 常熟生益科技有限公司 2024-03-22 CN disclosed
US-11898009-B2 Polyimide, laminate, and electronic device including same UBE CORPORATION (JP) 2024-02-13 US disclosed
US-5670609-A FILMS WITH LIQUID CCRYSTAL STRUCTURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-09-23 US disclosed
WO-1995015512-A1 POLY(2,6-PIPERAZINEDIONE) ALIGNMENT LAYER FOR LIQUID CRYSTAL DISPLAYS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-06-08 WO disclosed
EP-0603339-A1 POLYIMIDE COPOLYMERS CONTAINING 3,3',4,4'-TETRACARBOXYBIPHENYL DIANHYDRIDE (BPDA) MOIETIES AMOCO CORPORATION (US) 1994-06-29 EP disclosed
WO-1993006151-A1 POLYIMIDE COPOLYMERS CONTAINING 3,3',4,4'-TETRACARBOXYBIPHENYL DIANHYDRIDE (BPDA) MOIETIES AMOCO CORPORATION (US) 1993-04-01 WO disclosed
EP-0349010-A1 Polyimide copolymers NIPPON STEEL CHEMICAL CO., LTD. (JP) 1990-01-03 EP disclosed
EP-0330456-A1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORPORATION (JP) 1989-08-30 EP disclosed