⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23698 | 0.96 | — | — | |
| Ethane SCHEMBL8991520 | 0.92 | — | — | |
| Isobutane SCHEMBL27985829 | 0.92 | LMNA (0.35) | — | |
| SCHEMBL8991375 | 0.81 | — | — | |
| SCHEMBL28236051 | 0.76 | OPRM1 (0.40) | — | |
| SCHEMBL23091 | 0.74 | — | — | |
| SCHEMBL14834905 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL62097 | 0.72 | — | — | |
| SCHEMBL5512711 | 0.72 | LMNA (0.68) | — | |
| SCHEMBL1357221 | 0.72 | LMNA (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854923-A | Boron-containing tackifier for silicone rubber and preparation method and application thereof | 中国科学院化学研究所 | 2023-10-10 | — | — | CN | claimed |
| EP-1899317-A2 | ENANTIOMERS OF N,N-DIMETHYL-3-(2-THIENYL)-3-HYDROXYPROPANAMINE BORANE AS INTERMEDIATES IN THE SYNTHESIS OF DULOXETINE | Teva Pharmaceutical Industries Ltd (IL) | 2008-03-19 | — | — | EP | claimed |
| US-20080015362-A1 | Process for the preparation of optically active (S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine | TEVA PHARMACEUTICALS USA, INC. | 2008-01-17 | — | — | US | claimed |
| WO-2007123900-A2 | ENANTIOMERS OF N,N-DIMETHYL-3-(2-THIENYL)-3-HYDROXYPROPANAMINE BORANE AS INTERMEDIATES IN THE SYNTHESIS OF DULOXETINE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-11-01 | — | — | WO | claimed |
| US-20060069263-A1 | Process for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzo-thiazole | CHEMAGIS LTD. (IL) | 2006-03-30 | — | — | US | claimed |
| CN-116854923-A | Boron-containing tackifier for silicone rubber and preparation method and application thereof | 中国科学院化学研究所 | 2023-10-10 | — | — | CN | disclosed |
| CN-116855223-A | High-bonding-strength organic silicon bonding sealant and preparation method and application thereof | 中国科学院化学研究所 | 2023-10-10 | — | — | CN | disclosed |
| US-11008290-B2 | Halogenated quinoline derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-05-18 | — | — | US | disclosed |
| US-10736966-B2 | Brush-poly (glycoamidoamine)-lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-08-11 | — | — | US | disclosed |
| US-20180265475-A1 | HALOGENATED QUINOLINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-09-20 | — | — | US | disclosed |
| US-9840479-B2 | Polyamine-fatty acid derived lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-12-12 | — | — | US | disclosed |
| EP-3164379-A1 | POLYAMINE-FATTY ACID DERIVED LIPIDOIDS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2017-05-10 | — | — | EP | disclosed |
| EP-2114862-A1 | PROCESS FOR THE PREPARATION OF O-DESMETHYL VENLAFAXINE | Merck Generics (UK) Limited (GB) | 2009-11-11 | — | — | EP | disclosed |
| EP-2038281-A2 | NICOTINIC AGONISTS SELECTIVE FOR THE ALPHA7 RECEPTOR SUBTYPE, THE PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREFROM | Universita' degli Studi di Milano (IT) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008093142-A1 | PROCESS FOR THE PREPARATION OF O-DESMETHYL VENLAFAXINE | GENERICS [UK] LIMITED (GB) | 2008-08-07 | — | — | WO | disclosed |
| EP-1899317-A2 | ENANTIOMERS OF N,N-DIMETHYL-3-(2-THIENYL)-3-HYDROXYPROPANAMINE BORANE AS INTERMEDIATES IN THE SYNTHESIS OF DULOXETINE | Teva Pharmaceutical Industries Ltd (IL) | 2008-03-19 | — | — | EP | disclosed |
| US-20080015362-A1 | Process for the preparation of optically active (S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine | TEVA PHARMACEUTICALS USA, INC. | 2008-01-17 | — | — | US | disclosed |
| WO-2008000469-A2 | NICOTINIC AGONISTS SELECTIVE FOR THE ALPHA7 RECEPTOR SUBTYPE, THE PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREFROM | UNIVERSITA DEGLI STUDI DI MILANO (IT) | 2008-01-03 | — | — | WO | disclosed |
| WO-2007123900-A2 | ENANTIOMERS OF N,N-DIMETHYL-3-(2-THIENYL)-3-HYDROXYPROPANAMINE BORANE AS INTERMEDIATES IN THE SYNTHESIS OF DULOXETINE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-11-01 | — | — | WO | disclosed |
| US-20060069263-A1 | Process for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzo-thiazole | CHEMAGIS LTD. (IL) | 2006-03-30 | — | — | US | disclosed |