Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.48 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | CCNK | O75909 | 4/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.44 |
| ▸ | CDK2 | P24941 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214388 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM1AEHMT2RCOR1USP30 | |
| SCHEMBL889079 | 0.94 | USP30 (0.53) | USP30PIK3CDPIK3CACCNKCCNA2 | |
| SCHEMBL31460656 | 0.89 | CCNK (0.49) | USP30PIK3CDCCNKCCNA2CDK2 | |
| SCHEMBL28717093 | 0.89 | CCNK (0.49) | USP30PIK3CDCCNKCCNA2CDK2 | |
| SCHEMBL29494812 | 0.89 | CCNK (0.49) | USP30PIK3CDCCNKCCNA2CDK2 | |
| SCHEMBL29527460 | 0.89 | CCNK (0.49) | USP30PIK3CDCCNKCCNA2CDK2 | |
| SCHEMBL22787807 | 0.89 | CCNK (0.49) | USP30PIK3CDCCNKCCNA2CDK2 | |
| SCHEMBL23003081 | 0.86 | USP30 (0.55) | USP30PIK3CDCCNKCCNA2CDK2 | |
| SCHEMBL23003082 | 0.86 | USP30 (0.55) | USP30PIK3CDCCNKCCNA2CDK2 | |
| SCHEMBL31460649 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KDM1AEHMT2RCOR1USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076441-A1 | COMPOUNDS OF GCN2 MODULATORS | Alesta Therapeutics BV (NL) | 2025-04-10 | — | — | WO | disclosed |