Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.63 |
| ▸ | NPC1 | O15118 | 11/20 | 0.63 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755427 | 0.88 | NPC1 (0.67) | RAB9ANPC1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL31461061 | 0.84 | NPC1 (0.70) | RAB9ANPC1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL31461065 | 0.82 | NPC1 (0.67) | RAB9ANPC1SMN1; SMN2MAPTNR1H4 | |
| SCHEMBL31461071 | 0.81 | NPC1 (0.78) | RAB9ANPC1ACE2SMN1; SMN2MAPT | |
| SCHEMBL31461052 | 0.80 | KDM4E (0.64) | RAB9ANPC1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL388112 | 0.79 | HNF4A (0.61) | RAB9ANPC1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL6794827 | 0.79 | ALDH1A1 (0.60) | RAB9ANPC1SMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL31461063 | 0.78 | NPC1 (0.65) | RAB9ANPC1SMN1; SMN2MAPTNFKB1 | |
| SCHEMBL30102095 | 0.78 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL3737008 | 0.77 | SMN1; SMN2 (1.00) | RAB9ANPC1ACE2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638642-A | Bicyclic compounds, pharmaceutical composition and application thereof | 暨南大学 | 2025-03-18 | — | — | CN | disclosed |