SCHEMBL3146129

SCHEMBL3146129

CCCCCCCCn1c(S)nc2cc(OC)ccc21

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.53
MAPT P10636 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
TP53 P04637 2/20 0.47
TLR8 Q9NR97 2/20 0.47
PLA2G2A P14555 2/20 0.46
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45
ALDH1A1 P00352 2/20 0.44
POLB P06746 1/20 0.44
HTT P42858 1/20 0.44
NPC1 O15118 1/20 0.44
GAA P10253 2/20 0.43
RPS6KA5 O75582 1/20 0.43
KDM4E B2RXH2 1/20 0.42
HSD17B10 Q99714 1/20 0.42
DYRK1A Q13627 1/20 0.41
KCNH2 Q12809 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14557072 0.95 TDP1 (0.55) TDP1MAPTSMN1; SMN2TP53MAOA
SCHEMBL3136774 0.81 TLR8 (0.49) MAPTTP53TLR8
SCHEMBL29328857 0.80 TDP1 (0.74) TDP1MAPTSMN1; SMN2TP53TLR8
SCHEMBL15382597 0.77 TLR8 (0.68) TDP1MAPTSMN1; SMN2TP53TLR8
SCHEMBL10833410 0.77 TLR8 (0.68) TDP1MAPTSMN1; SMN2TP53TLR8
SCHEMBL3141446 0.77 TLR8 (0.68) TDP1MAPTSMN1; SMN2TP53TLR8
SCHEMBL3136462 0.77 TLR8 (0.68) TDP1MAPTSMN1; SMN2TP53TLR8
SCHEMBL22087155 0.76 MAOA (0.68) MAPTPLA2G2AMAOAMAOBALDH1A1
SCHEMBL22042200 0.76 MAOA (0.68) MAPTPLA2G2AMAOAMAOBALDH1A1
SCHEMBL3137088 0.76 TLR8 (0.68) TDP1MAPTSMN1; SMN2TP53TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 EP disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 US disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-20100075260-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
US-20090246700-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090246699-A1 PLATE-MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-1748317-B1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORP (JP) 2009-09-16 EP disclosed
EP-2090933-A1 Lithographic printing plate precursor and printing method FUJIFILM Corporation (JP) 2009-08-19 EP disclosed
US-20090197205-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-08-06 US disclosed
US-20090114108-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION (JP) 2009-05-07 US disclosed
EP-2006738-A2 Lithographic printing plate precursor and lithographic printing method Fujifilm Corporation (JP) 2008-12-24 EP disclosed