Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.49 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22965271 | 0.83 | TDP1 (0.61) | TDP1MAPTTP53LMNAKDM4E | |
| SCHEMBL26067835 | 0.82 | TDP1 (0.61) | TDP1MAPTTP53LMNAKDM4E | |
| SCHEMBL3146129 | 0.80 | TDP1 (0.53) | TDP1MAPTTP53KDM4EHSD17B10 | |
| SCHEMBL938178 | 0.79 | KDM4E (0.70) | TDP1MAPTTP53LMNAKDM4E | |
| SCHEMBL14344232 | 0.77 | MAPT (0.69) | TDP1MAPTTP53LMNAKDM4E | |
| SCHEMBL28500602 | 0.77 | ALDH1A1 (0.50) | TDP1MAPTTP53LMNAHSD17B10 | |
| SCHEMBL31121588 | 0.77 | KDM4E (0.64) | TDP1MAPTKDM4EHSD17B10NPC1 | |
| SCHEMBL11682381 | 0.77 | KDM4E (0.64) | TDP1MAPTKDM4EHSD17B10NPC1 | |
| SCHEMBL14557072 | 0.75 | TDP1 (0.55) | TDP1MAPTTP53LMNARPS6KA5 | |
| SCHEMBL1022300 | 0.75 | TLR8 (0.69) | TP53LMNAGAAHTTTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234609-B1 | METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS | POLYPLUS TRANSFECTION (FR) | 2024-07-17 | — | — | EP | disclosed |