Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9841111 | 0.83 | THRB (0.54) | THRBKDM4EHSD17B10LMNAMAPT | |
| Hydrochloric Acid SCHEMBL7967074 | 0.81 | THRB (0.52) | THRBKDM4EHSD17B10LMNAMAPT | |
| SCHEMBL14334370 | 0.78 | AKT1 (0.37) | THRBPREPKDM4EHSD17B10MAPT | |
| SCHEMBL1189236 | 0.78 | THRB (0.45) | THRBKDM4EHSD17B10LMNAMAPT | |
| SCHEMBL3784961 | 0.78 | THRB (0.45) | THRBKDM4EHSD17B10LMNATSHR | |
| SCHEMBL4644479 | 0.77 | GRM6 (0.43) | THRBPREPKDM4EHSD17B10LMNA | |
| SCHEMBL4058388 | 0.75 | CD44 (0.48) | THRBKDM4EHSD17B10LMNAMAPT | |
| SCHEMBL2636943 | 0.75 | THRB (0.71) | THRBMAPTCYP3A4TSHRMMP2 | |
| SCHEMBL30590428 | 0.75 | CD44 (0.48) | THRBKDM4EHSD17B10LMNAMAPT | |
| SCHEMBL3502815 | 0.75 | THRB (0.46) | THRBKDM4EHSD17B10LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |