Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HCN1 | O60741 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461693 | 0.89 | ALDH1A1 (0.44) | ALDH1A1HTTRIPK1KDM4ELMNA | |
| SCHEMBL30623744 | 0.89 | ALDH1A1 (0.40) | ALDH1A1HTTRIPK1KDM4ELMNA | |
| SCHEMBL31461717 | 0.89 | EGFR (0.42) | ALDH1A1HTTRIPK1KDM4ELMNA | |
| SCHEMBL26629778 | 0.89 | ALDH1A1 (0.40) | ALDH1A1HTTRIPK1KDM4ELMNA | |
| SCHEMBL31461721 | 0.87 | F2R (0.41) | ALDH1A1HTTRIPK1KDM4ELMNA | |
| SCHEMBL26601311 | 0.87 | POLB (0.38) | ALDH1A1HTTRIPK1LMNARAB9A | |
| SCHEMBL31675879 | 0.87 | POLB (0.38) | ALDH1A1HTTRIPK1LMNARAB9A | |
| SCHEMBL31461697 | 0.86 | ALDH1A1 (0.41) | ALDH1A1HTTRIPK1KDM4ELMNA | |
| SCHEMBL31461714 | 0.86 | ADRA2A (0.42) | ALDH1A1HTTRIPK1KDM4ELMNA | |
| SCHEMBL31461702 | 0.86 | ALDH1A1 (0.41) | ALDH1A1HTTRIPK1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024543-A1 | TRICYCLIC UBE2K MODULATORS AND METHODS FOR THEIR USE | BPGBIO, INC. (US) | 2025-01-30 | — | — | WO | disclosed |