Benzidine

Benzidine

SCHEMBL3146294

CCOCC.Nc1ccc(-c2ccc(N)cc2)cc1.O=P

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.50
TDP1 Q9NUW8 4/20 0.50
ALDH1A1 P00352 4/20 0.50
TP53 P04637 2/20 0.50
TSHR P16473 2/20 0.46
LMNA P02545 3/20 0.44
CYP1A2 P05177 1/20 0.44
MAOA P21397 1/20 0.44
MAPT P10636 4/20 0.42
HSD17B10 Q99714 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
GAA P10253 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 1/20 0.42
ALOX15 P16050 1/20 0.42
RAB9A P51151 1/20 0.42
TAAR1 Q96RJ0 2/20 0.42
KDM4E B2RXH2 2/20 0.41
MAPK1 P28482 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzidine SCHEMBL1056565 0.93 TDP1 (0.58) CYP3A4TDP1ALDH1A1TP53TSHR
Benzidine SCHEMBL28724222 0.91 TDP1 (0.55) CYP3A4TDP1ALDH1A1TP53TSHR
Biphenyl-4-Amine SCHEMBL8808746 0.84 TDP1 (0.65) CYP3A4TDP1ALDH1A1TP53TSHR
Ether SCHEMBL2211328 0.83 CYP3A4 (0.54) CYP3A4TDP1ALDH1A1TP53TSHR
Ether SCHEMBL7219756 0.82 MAOA (0.55) CYP3A4TDP1ALDH1A1TP53LMNA
Benzidine SCHEMBL7163808 0.82 MAOA (0.55) CYP3A4TDP1ALDH1A1TP53LMNA
Benzidine SCHEMBL10438317 0.82 PARP1 (0.41) CYP3A4TDP1ALDH1A1TP53TSHR
Benzidine SCHEMBL3420120 0.81 CYP3A4 (0.44) CYP3A4TDP1ALDH1A1TP53TSHR
Benzidine SCHEMBL3240163 0.81 CYP3A4 (0.49) CYP3A4TDP1ALDH1A1TP53TSHR
Benzidine SCHEMBL15658491 0.79 CYP3A4 (0.43) CYP3A4TDP1ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3368198-B1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF BLUESHIFT MAT INC (US) 2022-07-06 EP claimed
CN-108348871-B Highly branched, non-crosslinked aerogels, method for the production thereof and use thereof 蓝移材料有限公司 2021-11-05 CN claimed
WO-2018200838-A1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL HAVING MACROPORES, METHODS OF MAKING, AND USES THEREOF Blueshift Materials, Inc. (US) 2018-11-01 WO claimed
EP-3368198-A1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF Blueshift International Materials, Inc. (US) 2018-09-05 EP claimed
US-9963578-B2 Black polyimides and synthesis thereof NEXOLVE CORPORATION (US) 2018-05-08 US claimed
US-20170121483-A1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF Blueshift Materials, Inc. 2017-05-04 US claimed
WO-2017074751-A1 HIGHLY BRANCHED NON-CROSSLINKED AEROGEL, METHODS OF MAKING, AND USES THEREOF BLUESHIFT INTERNATIONAL MATERIALS, INC. (US) 2017-05-04 WO claimed
US-9562141-B2 Method of aerogel synthesis NEXOLVED CORPORATION (US) 2017-02-07 US claimed
EP-2999736-A1 METHOD OF AEROGEL SYNTHESIS NeXolve Corporation (US) 2016-03-30 EP claimed
US-20160075847-A1 Method of Aerogel Synthesis NEXOLVE HOLDING COMPANY, LLC 2016-03-17 US claimed
WO-2012103238-A2 POLYIMIDE POLYMER FROM NON-STOICHIOMETRIC COMPONENTS NEXOLVE CORPORATIOIN (US) 2012-08-02 WO claimed
US-20120190802-A1 POLYIMIDE POLYMER FROM NON-STOICHIOMETRIC COMPONENTS NEXOLVE CORPORATION (US) 2012-07-26 US claimed
US-7785517-B2 Methods for reducing or eliminating defects in polymer workpieces NEXOLVE CORPORATION (US) 2010-08-31 US claimed
WO-2009029582-A1 METHODS AND DEVICES FOR REDUCING OR ELIMINATING DEFECTS IN POLYMER WORKPIECES MANTECH SRS TECHNOLOGIES, INC. (US) 2009-03-05 WO claimed
US-20090054615-A1 Methods For Reducing Or Eliminating Defects In Polymer Workpieces BARINGS FINANCE LLC, AS COLLATERAL AGENT 2009-02-26 US claimed
EP-1395627-B1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH DU PONT (US) 2006-11-02 EP claimed
EP-1395627-A1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-03-10 EP claimed
US-6653433-B2 From polyamic acids E. I. DU PONT DE NEMOURS AND COMPANY 2003-11-25 US claimed
WO-2002090422-A1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-11-14 WO claimed
US-20020010311-A1 From polyamic acids E.I. DU PONT DE NEMOURS AND COMPANY 2002-01-24 US claimed