Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzidine SCHEMBL1056565 | 0.87 | TDP1 (0.58) | CYP3A4TDP1ALDH1A1TP53TSHR | |
| Benzidine SCHEMBL28724222 | 0.85 | TDP1 (0.55) | CYP3A4TDP1ALDH1A1TP53TSHR | |
| SCHEMBL3326593 | 0.82 | ALDH1A1 (0.65) | CYP3A4TDP1ALDH1A1TP53TSHR | |
| Benzidine SCHEMBL3146294 | 0.81 | CYP3A4 (0.50) | CYP3A4TDP1ALDH1A1TP53TSHR | |
| Biphenyl-4-Amine SCHEMBL8808746 | 0.79 | TDP1 (0.65) | CYP3A4TDP1ALDH1A1TP53TSHR | |
| Ether SCHEMBL2211328 | 0.78 | CYP3A4 (0.54) | CYP3A4TDP1ALDH1A1TP53TSHR | |
| SCHEMBL34346 | 0.75 | CYP3A4 (0.65) | CYP3A4TDP1ALDH1A1TP53TSHR | |
| Ether SCHEMBL7219756 | 0.73 | MAOA (0.55) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| Benzidine SCHEMBL7163808 | 0.73 | MAOA (0.55) | CYP3A4TDP1ALDH1A1TP53HSD17B10 | |
| SCHEMBL3781960 | 0.72 | TDP1 (0.50) | CYP3A4TDP1ALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152660-A2 | PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP | Rolic AG (CH) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008145225-A2 | PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP | ROLIC AG (CH) | 2008-12-04 | — | — | WO | disclosed |
| EP-1966119-A1 | PHOTOCROSSLINKABLE MATERIALS | Rolic AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071091-A1 | PHOTOCROSSLINKABLE MATERIALS | ROLIC AG (CH) | 2007-06-28 | — | — | WO | disclosed |