SCHEMBL31463672

SCHEMBL31463672

CCC1(c2ccc(Cl)nc2)CC1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.41
P2RX7 Q99572 6/20 0.37
MAPT P10636 1/20 0.37
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29275017 0.83 GRIN2D (0.39) DGAT1
SCHEMBL4050758 0.81 P2RX7 (0.42) P2RX7SLC6A4
SCHEMBL20489698 0.81 P2RX7 (0.36) DGAT1P2RX7SLC6A4SLC6A3
SCHEMBL19849282 0.77 P2RX7 (0.35) P2RX7
SCHEMBL15129177 0.75 SLC6A3 (0.59) P2RX7SLC6A4SLC6A3
SCHEMBL12248258 0.74 SLC6A4 (0.52) SLC6A4SLC6A3
SCHEMBL15129324 0.74 SLC6A3 (0.62) P2RX7SLC6A4SLC6A3
SCHEMBL23089394 0.72 P2RX7 (0.39) P2RX7
SCHEMBL15255154 0.72 DGAT1 (0.54) DGAT1MAPT
SCHEMBL29814481 0.72 P2RX7 (0.39) P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025024707-A1 INHIBITORS OF CDK2/4/6 KINASE KINNATE BIOPHARMA INC. (US) 2025-01-30 WO disclosed