Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.66 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.55 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.51 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.51 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.51 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.51 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999520 | 0.90 | MAPKAPK2 (0.54) | MAPKAPK2MAPK10ACVR1BTGFBR1BMPR1B | |
| SCHEMBL31464350 | 0.89 | MAPKAPK2 (0.53) | MAPKAPK2MAPK10ALKCDC7PIM1 | |
| SCHEMBL31464531 | 0.85 | MAPKAPK2 (0.67) | MAPKAPK2ACVR1ALK | |
| SCHEMBL20732829 | 0.84 | MAPKAPK2 (0.60) | MAPKAPK2MAPK10ACVR1BTGFBR1BMPR1B | |
| SCHEMBL28505160 | 0.84 | MAPKAPK2 (0.60) | MAPKAPK2MAPK10ACVR1BTGFBR1BMPR1B | |
| SCHEMBL28502016 | 0.82 | MAPKAPK2 (0.57) | MAPKAPK2MAPK10ACVR1BTGFBR1BMPR1B | |
| SCHEMBL20733053 | 0.81 | MAPKAPK2 (0.56) | MAPKAPK2MAPK10ACVR1BTGFBR1BMPR1B | |
| SCHEMBL20732831 | 0.80 | MAPKAPK2 (0.55) | MAPKAPK2MAPK10ACVR1BTGFBR1BMPR1B | |
| SCHEMBL20732830 | 0.78 | MAPKAPK2 (0.53) | MAPKAPK2MAPK10ACVR1BTGFBR1BMPR1B | |
| SCHEMBL20732922 | 0.78 | MAPKAPK2 (0.53) | MAPKAPK2MAPK10ACVR1BTGFBR1BMPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025064853-A1 | RIPK3 INHIBITORS AND METHODS OF USE | Momentum Therapeutics, Inc. (US) | 2025-03-27 | — | — | WO | disclosed |
| US-20250092031-A1 | RIPK3 INHIBITORS AND METHODS OF USE | INTEGRAL BIOSCIENCES PVT. LTD. (IN) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092031-A1 | RIPK3 INHIBITORS AND METHODS OF USE | RIPK3, RIPK1, RIPK2 | MAPKAPK2 169/4885MAPK10 1008/4885ACVR1B 3643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.