Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.62 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | RUNX1 | Q01196 | 4/20 | 0.48 |
| ▸ | CBFB | Q13951 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | QPCT | Q16769 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1266231 | 1.00 | MMP12 (0.62) | MMP12PRKCIRUNX1CBFBKDM4E | |
| SCHEMBL23636198 | 0.91 | MMP12 (0.55) | MMP12PRKCIRUNX1CBFBKDM4E | |
| SCHEMBL5046499 | 0.86 | MMP12 (0.45) | MMP12RUNX1CBFBKDM4EMAPT | |
| SCHEMBL21966110 | 0.83 | MMP12 (0.67) | MMP12PRKCIKDM4EMAPTRAD52 | |
| SCHEMBL9446008 | 0.79 | MMP12 (0.62) | MMP12PRKCIKDM4EMAPTRAD52 | |
| SCHEMBL28072848 | 0.78 | PARP1 (0.58) | ALOX15SMN1; SMN2 | |
| SCHEMBL225932 | 0.77 | MMP12 (1.00) | MMP12PRKCIKDM4EMAPTRAD52 | |
| SCHEMBL23636201 | 0.75 | MMP12 (0.60) | MMP12PRKCIKDM4EMAPTRAD52 | |
| SCHEMBL19093969 | 0.74 | RUNX1 (0.50) | RUNX1CBFBKDM4EKIF11TRPV1 | |
| SCHEMBL3162546 | 0.74 | MMP12 (0.69) | MMP12PRKCICBFBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672590-B1 | METHODS FOR INDUCING HEMATOPOIETIC STEM CELL SPECIFICITY | CHILDRENS MEDICAL CT CORP (US) | 2025-02-12 | — | — | EP | disclosed |
| US-12215351-B2 | Methods for inducing hematopoietic stem cell specificity | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12215351-B2 | Methods for inducing hematopoietic stem cell specificity | RUNX1, CBFB, MCL1 | MMP12 1080/4885PRKCI 565/4885RUNX1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.