Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.60 |
| ▸ | QPCT | Q16769 | 6/20 | 0.51 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30467970 | 1.00 | MMP12 (0.60) | MMP12QPCTCDK1POLBHTT | |
| SCHEMBL29488199 | 0.87 | TRPA1 (0.44) | MMP12QPCTCDK1POLBHTT | |
| SCHEMBL1799380 | 0.85 | MMP12 (0.62) | MMP12QPCTCDK1HTTSMN1; SMN2 | |
| SCHEMBL29770425 | 0.85 | MMP12 (0.62) | MMP12QPCTCDK1HTTSMN1; SMN2 | |
| SCHEMBL7013293 | 0.83 | PRKCI (0.66) | MMP12QPCTCDK1SMN1; SMN2PRKCI | |
| SCHEMBL30468011 | 0.83 | MMP12 (0.60) | MMP12QPCTCDK1POLBPRKCI | |
| SCHEMBL23636200 | 0.83 | MMP12 (0.60) | MMP12QPCTCDK1POLBPRKCI | |
| SCHEMBL23636198 | 0.83 | MMP12 (0.55) | MMP12QPCTCDK1PRKCIKDM4E | |
| SCHEMBL30468089 | 0.83 | MMP12 (0.55) | MMP12QPCTCDK1PRKCIKDM4E | |
| SCHEMBL12633977 | 0.83 | LTA4H (0.58) | MMP12QPCTCDK1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110612289-B | Deuterated benzimidazole compound and medical application thereof | 住友制药株式会社 | 2023-06-30 | — | — | CN | disclosed |
| US-11066372-B2 | Deuterated benzimidazole compound and medical use thereof | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-07-20 | — | — | US | disclosed |
| US-11066372-B2 | Deuterated benzimidazole compound and medical use thereof | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-07-20 | — | — | US | disclosed |
| CN-110612289-A | Deuterated benzimidazole compounds and medical application thereof | 大日本住友制药株式会社 | 2019-12-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11066372-B2 | Deuterated benzimidazole compound and medical use thereof | HCN4, HCN3, SCN8A | MMP12 3736/4885QPCT 2835/4885CDK1 827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.