Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13822288 | 0.76 | KDR (0.68) | PLK4AURKADYRK3MAP4K4NTRK1 | |
| SCHEMBL31465408 | 0.75 | KIT (0.42) | NTRK1MEN1MAPTKMT2AALDH2 | |
| SCHEMBL2227680 | 0.75 | PLK4 (0.48) | PLK4AURKADYRK3MAP4K4NTRK1 | |
| SCHEMBL30065084 | 0.72 | MEN1 (0.41) | MKNK2MEN1MAPTKMT2AALDH2 | |
| SCHEMBL6640497 | 0.68 | KMT2A (0.49) | MEN1MAPTKMT2AALDH2L3MBTL1 | |
| SCHEMBL31465372 | 0.68 | L3MBTL1 (0.43) | MEN1MAPTKMT2AALDH2L3MBTL1 | |
| SCHEMBL2284618 | 0.67 | PRKAB2 (0.65) | PLK4AURKADYRK3MAP4K4NTRK1 | |
| SCHEMBL16111648 | 0.67 | MAP4K4 (0.43) | PLK4AURKADYRK3MAP4K4NTRK1 | |
| SCHEMBL16112670 | 0.65 | PRKAB2 (0.50) | PLK4AURKADYRK3MAP4K4NTRK1 | |
| SCHEMBL31638065 | 0.65 | MEN1 (0.44) | MEN1MAPTKMT2AALDH2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068090-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES | GALAPAGOS NV (BE) | 2025-04-03 | — | — | WO | disclosed |