Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31465490 | 0.85 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL31465455 | 0.83 | MEN1 (0.38) | MEN1KMT2ANTRK1ALDH1A1 | |
| SCHEMBL31668760 | 0.76 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1 | |
| SCHEMBL27166380 | 0.74 | MEN1 (0.45) | MEN1KMT2A | |
| SCHEMBL31465524 | 0.72 | MEN1 (0.49) | MEN1KMT2ANTRK1ALDH1A1 | |
| SCHEMBL27166510 | 0.72 | MEN1 (0.49) | MEN1KMT2ANTRK1ALDH1A1 | |
| SCHEMBL27224976 | 0.69 | MAPK8 (0.43) | MEN1KMT2A | |
| SCHEMBL25210271 | 0.67 | GSK3A (0.43) | — | |
| SCHEMBL30396166 | 0.67 | GSK3A (0.43) | — | |
| SCHEMBL31465472 | 0.64 | IRAK4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049253-A1 | BRIDGED CYCLE‑BASED INHIBITORS OF DNA‑DEPENDENT PROTEIN KINASE AND COMPOSITIONS AND APPLICATION IN GENE EDITING | JUNO THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |