SCHEMBL31465702

SCHEMBL31465702

C/C(=N\O)C(=O)Nc1c(C)cc(O)cc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
HTT P42858 2/20 0.38
HPGD P15428 1/20 0.38
PTPRB P23467 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP3A4 P08684 3/20 0.38
CHRM1 P11229 1/20 0.38
ALOX15 P16050 1/20 0.38
MAOA P21397 1/20 0.38
TBXA2R P21731 1/20 0.38
ADRA1A P35348 1/20 0.38
HTR2B P41595 1/20 0.38
LMNA P02545 3/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CYTH2 Q99418 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18415453 0.82 ALDH1A1 (0.63) ALDH1A1HPGDCYP3A4CHRM1ALOX15
SCHEMBL31465693 0.81 HPGD (0.45) ALDH1A1HTTHPGDPTPRBHSD17B10
SCHEMBL31465689 0.80 ALDH1A1 (0.56) ALDH1A1HTTCYP3A4ALOX15HTR2B
SCHEMBL27780197 0.78 ALDH1A1 (0.48) ALDH1A1HPGDPTPRBHSD17B10CYP3A4
SCHEMBL29035952 0.77 ALDH1A1 (0.52) ALDH1A1HPGDPTPRBHSD17B10CYP3A4
SCHEMBL20857699 0.77 LMNA (0.56) ALDH1A1HTTHPGDPTPRBHSD17B10
SCHEMBL28391937 0.76 ALDH1A1 (0.50) ALDH1A1CYP3A4CHRM1ALOX15MAOA
SCHEMBL19857150 0.74 CYTH2 (0.48) ALDH1A1HPGDPTPRBHSD17B10CYP3A4
SCHEMBL31465665 0.71 ALDH1A1 (0.46) ALDH1A1CYP3A4ALOX15HTR2BLMNA
SCHEMBL24849174 0.70 LMNA (0.49) ALDH1A1HPGDCYP3A4CHRM1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025056724-A1 IMINOAMIDE-TYPE COMPOUNDS AS LIGANDS FOR COPPER-CATALYZED COUPLING REACTIONS OF (HETERO)ARYL HALIDES BAYER AKTIENGESELLSCHAFT (DE) 2025-03-20 WO disclosed