Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 3/20 | 0.45 |
| ▸ | HTR3A | P46098 | 6/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.43 |
| ▸ | HTR3B | O95264 | 3/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31466522 | 0.82 | ALDH1A1 (0.44) | SIGMAR1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL31466203 | 0.81 | CACNA1B (0.44) | MAPKAPK2ALDH1A1 | |
| SCHEMBL31466011 | 0.78 | CACNB4 (0.46) | HTTSMN1; SMN2 | |
| SCHEMBL8326134 | 0.76 | BPTF (0.62) | BPTFHTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL31465933 | 0.71 | ADRB1 (0.56) | BPTFHTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL6359735 | 0.70 | BPTF (0.56) | BPTFHTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL31466176 | 0.70 | PRCP (0.52) | — | |
| SCHEMBL14529228 | 0.70 | MAP4K4 (0.34) | SIGMAR1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL31466136 | 0.69 | CACNB4 (0.47) | HTTSMN1; SMN2 | |
| SCHEMBL31466010 | 0.69 | PRCP (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |