Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31465948 | 0.82 | BPTF (0.45) | ALDH1A1HTTSMN1; SMN2SIGMAR1 | |
| SCHEMBL31465999 | 0.76 | SIGMAR1 (0.54) | SIGMAR1KDM4E | |
| SCHEMBL31466011 | 0.75 | CACNB4 (0.46) | HTTSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL31466010 | 0.73 | PRCP (0.51) | — | |
| SCHEMBL31466176 | 0.73 | PRCP (0.52) | — | |
| SCHEMBL31466203 | 0.68 | CACNA1B (0.44) | ALDH1A1HSD17B10HPGDKDM4ENPC1 | |
| SCHEMBL11981452 | 0.67 | ALDH1A1 (0.64) | ALDH1A1HTTSMN1; SMN2HSD17B10HPGD | |
| SCHEMBL13212651 | 0.67 | CNR2 (0.54) | ALDH1A1SIGMAR1KDM4ENPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL27696045 | 0.66 | ALDH1A1 (0.62) | ALDH1A1HTTSMN1; SMN2HSD17B10HPGD | |
| SCHEMBL14545307 | 0.66 | KDM4E (0.46) | ALDH1A1HTTKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |