Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.46 |
| ▸ | BCR | P11274 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31466504 | 0.91 | SLC6A4 (0.43) | SIGMAR1 | |
| SCHEMBL31466012 | 0.90 | SIGMAR1 (0.44) | ABL1BCRSIGMAR1HTR2BKCNH2 | |
| SCHEMBL31465969 | 0.89 | ABL1 (0.42) | ABL1BCRSIGMAR1HTR2BKCNH2 | |
| SCHEMBL31466390 | 0.89 | ABL1 (0.42) | ABL1BCRSIGMAR1HTR2BKCNH2 | |
| SCHEMBL31465965 | 0.88 | DRD2 (0.37) | ABL1BCRSIGMAR1KCNH2GAA | |
| SCHEMBL31466209 | 0.88 | CARM1 (0.37) | ABL1BCRSIGMAR1KCNH2GAA | |
| SCHEMBL31466132 | 0.88 | ABL1 (0.43) | ABL1BCRBRD4GAAMAPK1 | |
| SCHEMBL31466588 | 0.87 | SIGMAR1 (0.45) | ABL1BCRSIGMAR1BRD4GAA | |
| SCHEMBL31466264 | 0.87 | ABL1 (0.42) | ABL1BCRBRD4GAAMAPK1 | |
| SCHEMBL31466107 | 0.86 | SIGMAR1 (0.44) | ABL1BCRSIGMAR1HTR2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |