Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31466615 | 0.90 | SIGMAR1 (0.45) | SIGMAR1KDM4EKCNH2HTR2B | |
| SCHEMBL31465985 | 0.86 | ABL1 (0.46) | SIGMAR1KCNH2HTR2BABL1BCR | |
| SCHEMBL31465869 | 0.85 | SIGMAR1 (0.52) | SIGMAR1CYP2C19KCNH2HTR2BDRD2 | |
| SCHEMBL31465843 | 0.85 | SIGMAR1 (0.47) | SIGMAR1KDM4EKCNH2HTR2B | |
| SCHEMBL31465980 | 0.82 | SIGMAR1 (0.44) | SIGMAR1KCNH2HTR2B | |
| SCHEMBL31466412 | 0.80 | KDM4E (0.46) | SIGMAR1KDM4ECYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31466526 | 0.78 | DRD2 (0.40) | SIGMAR1KCNH2HTR2BDRD2 | |
| SCHEMBL31465877 | 0.78 | HTR2C (0.49) | SIGMAR1 | |
| SCHEMBL31466504 | 0.77 | SLC6A4 (0.43) | SIGMAR1 | |
| SCHEMBL31466132 | 0.76 | ABL1 (0.43) | ABL1BCRDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049419-A1 | PYRAZOLYL COMPOUNDS AS EMOPAMIL BINDING PROTEIN INHIBITORS | GENZYME CORPORATION (US) | 2025-03-06 | — | — | WO | disclosed |