Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 3/20 | 0.51 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 2/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16028419 | 1.00 | TRPC5 (0.51) | TRPC5TRPC4KCNH2BRAFPIK3CG | |
| SCHEMBL30171360 | 0.92 | TRPC5 (0.51) | TRPC5TRPC4KCNH2HPGDTRPC1 | |
| SCHEMBL16028606 | 0.92 | TRPC5 (0.51) | TRPC5TRPC4KCNH2HPGDTRPC1 | |
| SCHEMBL20432632 | 0.90 | ADORA2B (0.53) | BRAFRAB9AADORA3HPGDALDH1A1 | |
| SCHEMBL16027905 | 0.90 | TRPC5 (0.54) | TRPC5TRPC4KCNH2BRAFPIK3CG | |
| SCHEMBL31466662 | 0.90 | TRPC5 (0.54) | TRPC5TRPC4KCNH2BRAFPIK3CG | |
| SCHEMBL16028882 | 0.90 | TRPC5 (0.54) | TRPC5TRPC4KCNH2BRAFPIK3CG | |
| SCHEMBL31466659 | 0.90 | TRPC5 (0.54) | TRPC5TRPC4KCNH2BRAFPIK3CG | |
| SCHEMBL16028313 | 0.87 | TRPC5 (0.52) | TRPC5TRPC4KCNH2BRAFPIK3CG | |
| SCHEMBL16027648 | 0.86 | TRPC5 (0.48) | TRPC5TRPC4KCNH2TRPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250034143-A1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES, LLC (US) | 2025-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250034143-A1 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | TRPC5, TRPC7, TRPC4 | TRPC5 1/4885TRPC4 3/4885KCNH2 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.