Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31612960 | 1.00 | ACHE (0.39) | ACHEALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL28331707 | 0.79 | CYP19A1 (0.43) | ACHEALDH1A1KDM4EL3MBTL1HPGD | |
| Hydrogen Sulfide SCHEMBL28333201 | 0.77 | CYP19A1 (0.42) | ACHEALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL141853 | 0.77 | ACHE (0.44) | ACHEALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL29793327 | 0.76 | ACHE (0.52) | ACHEALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL1635785 | 0.76 | ACHE (0.52) | ACHEALDH1A1KDM4EL3MBTL1TSHR | |
| Ammonia Solution, Strong SCHEMBL27342870 | 0.75 | ALDH1A1 (0.44) | ACHEALDH1A1KDM4EL3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL9739649 | 0.75 | ACHE (0.42) | ACHEALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL31186207 | 0.73 | TSHR (0.36) | ACHETSHRPOLBLMNA | |
| SCHEMBL8917666 | 0.73 | TSHR (0.36) | ACHETSHRPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025119300-A1 | MYT1 KINASE INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 广东东阳光药业股份有限公司 | 2025-06-12 | — | — | WO | disclosed |
| CN-120118088-A | Myt1 kinase inhibitor compounds, pharmaceutical compositions thereof and uses thereof | 广东东阳光药业股份有限公司 | 2025-06-10 | — | — | CN | disclosed |
| WO-2025064567-A1 | TRICYCLIC PHENOLS FOR INHIBITION OF RAF KINASES | ENLIVEN INC. (US) | 2025-03-27 | — | — | WO | disclosed |