SCHEMBL8917666

SCHEMBL8917666

Cc1ccc(C)c(I)c1C

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2A6 P11509 1/20 0.36
TDP2 O95551 1/20 0.36
NSD2 O96028 1/20 0.36
HSP90AA1 P07900 1/20 0.36
PAX8 Q06710 1/20 0.36
POLB P06746 1/20 0.33
TRPA1 O75762 1/20 0.33
ATM Q13315 1/20 0.33
ACHE P22303 2/20 0.32
MCL1 Q07820 1/20 0.31
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31186207 1.00 TSHR (0.36) TSHRCYP1A2CYP2A6TDP2NSD2
SCHEMBL7626926 0.82 CYP1A2 (0.39) TSHRCYP1A2CYP2A6POLBACHE
SCHEMBL6858668 0.81 CYP1A2 (0.33) TSHRCYP1A2CYP2A6TDP2NSD2
SCHEMBL21624583 0.81 POLB (0.31) CYP1A2POLB
SCHEMBL22606956 0.81 POLB (0.48) CYP1A2TDP2NSD2HSP90AA1PAX8
SCHEMBL24940926 0.77 TRPA1 (0.44) TSHRCYP1A2TRPA1ATMACHE
SCHEMBL9229801 0.77 CYP3A4 (0.39) TSHRCYP1A2CYP2A6TDP2NSD2
SCHEMBL16970797 0.77 CYP3A4 (0.43) TSHRPOLBNOS3NOS2
SCHEMBL9720717 0.77 TDP2 (0.31) TDP2NSD2HSP90AA1PAX8
SCHEMBL19812690 0.77 ALDH1A1 (0.36) TDP2NSD2HSP90AA1PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483581-B Palladium complex containing diphosphine m-carborane ligand and preparation and application thereof 上海应用技术大学 2021-05-11 CN claimed
WO-2024061796-A1 POLYMERISABLE LIQUID CRYSTAL MEDIUM AND POLYMERISED LIQUID CRYSTAL FILM MERCK PATENT GMBH (DE) 2024-03-28 WO disclosed
WO-2024042008-A1 POLYMERIZABLE LIQUID CRYSTAL MATERIAL AND POLYMERIZED LIQUID CRYSTAL FILM MERCK PATENT GMBH (DE) 2024-02-29 WO disclosed
EP-3668948-B1 POLYMERISABLE LIQUID CRYSTAL MATERIAL AND POLYMERISED LIQUID CRYSTAL FILM MERCK PATENT GMBH (DE) 2023-10-25 EP disclosed
US-11781069-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2023-10-10 US disclosed
US-20230263057-A1 LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE SAME, AND THE CONDENSED CYCLIC COMPOUND SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-17 US disclosed
US-11706983-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-20230183571-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-06-15 US disclosed
WO-2023061903-A1 POLYMERISABLE COMPOUND, POLYMERISABLE LC MATERIAL AND POLYMER FILM MERCK PATENT GMBH (DE) 2023-04-20 WO disclosed
EP-3784755-B1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2022-06-15 EP disclosed
EP-3049506-B1 COMPOUNDS AND MESOGENIC MEDIA MERCK PATENT GMBH (DE) 2017-06-14 EP disclosed
WO-2017071793-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2017-05-04 WO disclosed
EP-2990459-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2017-04-26 EP disclosed
WO-2017045740-A1 LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT MERCK PATENT GMBH (DE) 2017-03-23 WO disclosed
WO-2017041893-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-03-16 WO disclosed
EP-3130651-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2017-02-15 EP disclosed
EP-2935514-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2017-02-01 EP disclosed
EP-2922933-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2017-02-01 EP disclosed
US-5616441-A AS ELECTRON TRANSFERRING COMPOUND; INCREASED PHOTOSENSITIVITY; WEAR AND HEAT RESISTANCE; SOLVENT SOLUBILITY; BINDER COMPATABILITY; COPIERS; LASER PRINTERS MITA INDUSTRIAL CO., LTD. (JP) 1997-04-01 US disclosed
EP-0708375-A1 Tryptanthrine derivative and electrophotosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1996-04-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230263057-A1 LIGHT-EMITTING DEVICE INCLUDING CONDENSED CYCLIC COMPOUND, ELECTRONIC APPARATUS INCLUDING THE SAME, AND THE CONDENSED CYCLIC COMPOUND CRY1, CCNE2, CRY2 TSHR 4581/4885CYP1A2 1605/4885CYP2A6 2900/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.