Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 3/20 | 0.33 |
| ▸ | BRS3 | P32247 | 7/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31467632 | 0.86 | TRPV4 (0.38) | TRPV4CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL31467597 | 0.83 | TRPV4 (0.40) | TRPV4CYP3A4CYP2C9CYP2C19PDCD1LG2 | |
| SCHEMBL31467641 | 0.83 | TRPV4 (0.41) | TRPV4CYP3A4CYP2C9CYP2C19USP2 | |
| SCHEMBL31467604 | 0.81 | TRPV4 (0.40) | TRPV4CYP2D6RORCBRS3NR1I2 | |
| SCHEMBL31467606 | 0.79 | PTGS1 (0.39) | TRPV4RORC | |
| SCHEMBL31467634 | 0.79 | TRPV4 (0.39) | TRPV4 | |
| SCHEMBL31467635 | 0.79 | TRPV4 (0.39) | TRPV4CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL31467621 | 0.79 | TRPV4 (0.39) | TRPV4CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL25371906 | 0.78 | TRPV4 (0.44) | TRPV4CYP2D6GAAALDH1A1BRS3 | |
| SCHEMBL30567044 | 0.78 | TRPV4 (0.44) | TRPV4CYP2D6GAAALDH1A1BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049275-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2025-03-06 | — | — | WO | disclosed |