Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 7/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 5/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 5/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 5/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 5/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 5/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 5/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | CCR9 | P51686 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 4/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31467620 | 0.87 | TRPV4 (0.41) | TRPV4PPARDRORCPIK3CATLR7 | |
| SCHEMBL31467598 | 0.83 | TRPV4 (0.41) | TRPV4RORC | |
| SCHEMBL31467569 | 0.82 | KDM4E (0.42) | PTGS2TRPV4CCR9 | |
| SCHEMBL31467634 | 0.82 | TRPV4 (0.39) | PTGS1PTGS2TRPV4TLR7 | |
| SCHEMBL31467643 | 0.82 | CYP3A4 (0.47) | TRPV4 | |
| SCHEMBL31467604 | 0.81 | TRPV4 (0.40) | TRPV4RORC | |
| SCHEMBL31467644 | 0.79 | TRPV4 (0.40) | TRPV4RORC | |
| SCHEMBL31467601 | 0.79 | TRPV4 (0.37) | TRPV4RORC | |
| SCHEMBL25371906 | 0.79 | TRPV4 (0.44) | TRPV4 | |
| SCHEMBL30567044 | 0.79 | TRPV4 (0.44) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049275-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2025-03-06 | — | — | WO | disclosed |