Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
| ▸ | PARG | Q86W56 | 11/20 | 0.36 |
| ▸ | RORC | P51449 | 6/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31467620 | 0.86 | TRPV4 (0.41) | TRPV4RORCCYP2D6 | |
| SCHEMBL31467598 | 0.86 | TRPV4 (0.41) | TRPV4BRS3RORCCYP2D6 | |
| SCHEMBL31467643 | 0.85 | CYP3A4 (0.47) | TRPV4CYP2D6 | |
| SCHEMBL31467644 | 0.84 | TRPV4 (0.40) | TRPV4NR1I2BRS3RORCCYP2D6 | |
| SCHEMBL31467569 | 0.83 | KDM4E (0.42) | TRPV4NR1I2BRS3CYP2D6 | |
| SCHEMBL25371906 | 0.82 | TRPV4 (0.44) | TRPV4NR1I2BRS3CYP2D6 | |
| SCHEMBL30567044 | 0.82 | TRPV4 (0.44) | TRPV4NR1I2BRS3CYP2D6 | |
| SCHEMBL31467594 | 0.82 | TRPV4 (0.45) | TRPV4RORCCYP2D6 | |
| SCHEMBL31467618 | 0.82 | TRPV4 (0.39) | TRPV4NR1I2BRS3PARGRORC | |
| SCHEMBL31467616 | 0.82 | TRPV4 (0.39) | TRPV4NR1I2BRS3RORCCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049275-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2025-03-06 | — | — | WO | disclosed |