Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CCR9 | P51686 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31467598 | 0.89 | TRPV4 (0.41) | ALDH1A1TRPV4BRS3USP2CYP2D6 | |
| SCHEMBL31467643 | 0.88 | CYP3A4 (0.47) | KDM4EALDH1A1TRPV4POLBTP53 | |
| SCHEMBL31467620 | 0.85 | TRPV4 (0.41) | ALDH1A1TRPV4USP2CYP2D6 | |
| SCHEMBL31467635 | 0.84 | TRPV4 (0.39) | ALDH1A1TRPV4PTGS2CYP2D6 | |
| SCHEMBL31467604 | 0.83 | TRPV4 (0.40) | TRPV4NR1I2BRS3CYP2D6 | |
| SCHEMBL31467631 | 0.82 | ACKR3 (0.41) | TRPV4PTGS2 | |
| SCHEMBL31467606 | 0.82 | PTGS1 (0.39) | TRPV4CCR9PTGS2 | |
| SCHEMBL31467644 | 0.82 | TRPV4 (0.40) | TRPV4NR1I2BRS3USP2CYP2D6 | |
| SCHEMBL31467610 | 0.82 | ALDH1A1 (0.46) | KDM4EALDH1A1TRPV4MMP1MMP3 | |
| SCHEMBL25371906 | 0.81 | TRPV4 (0.44) | KDM4EALDH1A1TRPV4POLBNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049275-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2025-03-06 | — | — | WO | disclosed |