Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 11/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 10/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 8/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31467598 | 0.89 | TRPV4 (0.41) | CYP3A4CYP2C9CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL31467569 | 0.88 | KDM4E (0.42) | CYP2D6ALDH1A1USP2TRPV4TP53 | |
| SCHEMBL31467620 | 0.87 | TRPV4 (0.41) | CYP3A4CYP2C9CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL31467635 | 0.85 | TRPV4 (0.39) | CYP3A4CYP2C9CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL31467604 | 0.85 | TRPV4 (0.40) | CYP2D6TRPV4 | |
| SCHEMBL31467644 | 0.85 | TRPV4 (0.40) | CYP3A4CYP2D6USP2TRPV4 | |
| SCHEMBL25371906 | 0.85 | TRPV4 (0.44) | CYP2D6ALDH1A1TRPV4KDM4EPOLB | |
| SCHEMBL30567044 | 0.85 | TRPV4 (0.44) | CYP2D6ALDH1A1TRPV4KDM4EPOLB | |
| SCHEMBL31467629 | 0.84 | TRPV4 (0.40) | CYP3A4USP2TRPV4KDM4EKMT2A | |
| SCHEMBL31467641 | 0.83 | TRPV4 (0.41) | CYP3A4CYP2C9CYP2D6CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049275-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2025-03-06 | — | — | WO | disclosed |