SCHEMBL31467771

SCHEMBL31467771

N=C(N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PRCP P42785 2/20 0.43
▸ OPRM1 P35372 8/20 0.42
▸ OPRK1 P41145 8/20 0.42
▸ ACE P12821 2/20 0.41
▸ EPHA2 P29317 2/20 0.40
▸ CTRB1 P17538 1/20 0.40
▸ F2 P00734 1/20 0.39
▸ LMNA P02545 1/20 0.39
▸ NMUR2 Q9GZQ4 1/20 0.39
▸ NMUR1 Q9HB89 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31437182 0.95 F2 (0.41) PRCPOPRM1OPRK1ACEEPHA2
SCHEMBL29561678 0.92 CTRB1 (0.42) PRCPOPRM1OPRK1CTRB1F2
SCHEMBL31437193 0.91 PRCP (0.51) PRCPACE
SCHEMBL31437183 0.91 PRCP (0.43) PRCPOPRM1OPRK1ACEEPHA2
SCHEMBL31467758 0.91 PRCP (0.46) PRCPOPRM1OPRK1ACEEPHA2
SCHEMBL31467760 0.88 PRCP (0.45) PRCPOPRM1OPRK1ACEEPHA2
SCHEMBL31437172 0.87 PRCP (0.44) PRCPOPRM1OPRK1ACE
SCHEMBL31437170 0.86 EPHA2 (0.44) PRCPOPRM1OPRK1EPHA2
SCHEMBL31437210 0.86 ACE (0.44) PRCPOPRM1OPRK1ACEEPHA2
SCHEMBL9815799 0.85 OPRM1 (0.49) PRCPOPRM1OPRK1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025037992-A1 NEW PEPTIDES AND USE THEREOF MAJEWSKI FILIP (PL) 2025-02-20 — — WO disclosed
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