Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 2/20 | 0.45 |
| ▸ | PRCP | P42785 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561225 | 0.96 | PRCP (0.46) | OPRM1OPRK1F2PRSS1PRCP | |
| SCHEMBL31437210 | 0.91 | ACE (0.44) | OPRM1OPRK1STAT6F2PRSS1 | |
| SCHEMBL31437193 | 0.87 | PRCP (0.51) | PRCP | |
| SCHEMBL30540072 | 0.87 | OPRM1 (0.50) | OPRM1OPRK1OPRD1F2 | |
| SCHEMBL31467758 | 0.87 | PRCP (0.46) | OPRM1OPRK1PRCP | |
| SCHEMBL31467771 | 0.85 | PRCP (0.43) | OPRM1OPRK1F2PRCP | |
| SCHEMBL9815839 | 0.85 | F2 (0.62) | OPRM1OPRK1F2PRSS1 | |
| SCHEMBL31437183 | 0.84 | PRCP (0.43) | OPRM1OPRK1F2PRCP | |
| SCHEMBL29812564 | 0.84 | PRCP (0.43) | OPRM1OPRK1PRCP | |
| SCHEMBL29561678 | 0.84 | CTRB1 (0.42) | OPRM1OPRK1F2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235692-B1 | OLIGOPEPTIDYL NITRILE DERIVATIVES, THE AGENTS CONTAINING THEM, PROCESS FOR THEIR PREPARATION AND THEIR USE | BEHRINGWERKE Aktiengesellschaft (DE) | 1991-11-06 | — | — | EP | disclosed |
| US-4927809-A | ANTICOAGULANTS | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1990-05-22 | — | — | US | disclosed |
| EP-0235692-A2 | Oligopeptidyl nitrile derivatives, the agents containing them, process for their preparation and their use | BEHRINGWERKE Aktiengesellschaft (DE) | 1987-09-09 | — | — | EP | disclosed |