SCHEMBL31468258

SCHEMBL31468258

Clc1ccc([Si](c2ccccc2)(c2ccccc2)c2cccc(Br)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
KDM4E B2RXH2 1/20 0.36
TP53 P04637 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
CYP1A2 P05177 1/20 0.35
GRIK1 P39086 2/20 0.35
GRIK2 Q13002 1/20 0.35
FLT1 P17948 1/20 0.35
FLT4 P35916 1/20 0.35
KDR P35968 1/20 0.35
GCGR P47871 1/20 0.35
MAPK14 Q16539 1/20 0.35
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31468257 0.89 TSHR (0.36) MEN1KMT2AALDH1A1TSHRNPC1
SCHEMBL4300967 0.88 ALDH1A1 (0.46) MEN1KMT2AALDH1A1TSHRNPC1
SCHEMBL5919703 0.88 ALDH1A1 (0.46) MEN1KMT2AALDH1A1TSHRNPC1
SCHEMBL31167613 0.88 ALDH1A1 (0.46) MEN1KMT2AALDH1A1TSHRNPC1
SCHEMBL31468245 0.84 ALDH1A1 (0.42) MEN1KMT2AALDH1A1TSHRNPC1
SCHEMBL25056770 0.83 ALDH1A1 (0.46) MEN1KMT2AALDH1A1TSHRNPC1
SCHEMBL15661564 0.82 TSHR (0.53) MEN1KMT2ATSHRNPC1RAB9A
SCHEMBL4876931 0.82 ALDH1A1 (0.46) MEN1KMT2AALDH1A1TSHRNPC1
SCHEMBL31468260 0.81 PGR (0.38) MEN1KMT2AALDH1A1TSHRNPC1
SCHEMBL14935535 0.80 ABCG2 (0.36) MEN1KMT2AALDH1A1TSHRNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025048507-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 2025-03-06 WO disclosed