Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956963 | 0.84 | ENPP2 (0.43) | ALDH1A1LMNAENPP2KDM4ETTR | |
| SCHEMBL29953019 | 0.82 | CSNK2A1 (0.44) | ALDH1A1LMNAENPP2KDM4ETTR | |
| SCHEMBL4881084 | 0.82 | CSNK2A1 (0.44) | ALDH1A1LMNAENPP2KDM4ETTR | |
| SCHEMBL2561475 | 0.81 | L3MBTL1 (0.46) | ALDH1A1LMNAENPP2KDM4ETTR | |
| SCHEMBL880121 | 0.80 | APP (0.40) | ALDH1A1LMNAENPP2KDM4ETTR | |
| SCHEMBL8955786 | 0.80 | ALDH1A1 (0.69) | ALDH1A1LMNAKDM4ECYP2C19MAPK1 | |
| SCHEMBL2551648 | 0.78 | UTS2R (0.46) | ALDH1A1LMNAENPP2KDM4EMAPK1 | |
| SCHEMBL2854999 | 0.78 | ENPP2 (0.46) | ALDH1A1LMNAENPP2TTRPOLB | |
| SCHEMBL29956646 | 0.78 | ENPP2 (0.46) | ALDH1A1LMNAENPP2TTRPOLB | |
| SCHEMBL23363515 | 0.74 | ENPP2 (0.43) | ALDH1A1LMNAENPP2TTRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684313-A | Macrocyclic compound and preparation method and application thereof | 上海爱科百发生物医药技术股份有限公司 | 2025-03-25 | — | — | CN | disclosed |