Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31469393 | 0.78 | TDP2 (0.38) | TDP2METAP2METAP1PDE10AECE1 | |
| SCHEMBL31469325 | 0.71 | KDM4E (0.41) | TDP2METAP1KDM4AALDH1A1 | |
| SCHEMBL31469335 | 0.69 | CSNK1D (0.48) | FLT3SYKAURKBCSNK1DCSNK1E | |
| SCHEMBL2047756 | 0.68 | LMNA (0.39) | PDE10AECE1 | |
| SCHEMBL19806539 | 0.67 | TGFBR1 (0.52) | METAP2PDE10A | |
| SCHEMBL25321979 | 0.63 | CSNK1D (0.64) | AURKBCSNK1D | |
| SCHEMBL953920 | 0.63 | COMT (0.36) | ALDH1A1 | |
| SCHEMBL7964249 | 0.62 | TSHR (0.50) | TDP2METAP2METAP1KDM4AKDM4B | |
| SCHEMBL243089 | 0.62 | — | — | |
| SCHEMBL13874035 | 0.61 | JMJD6 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029158-A | EGFR inhibitors | 缆图药品公司 | 2026-05-12 | — | — | CN | disclosed |
| WO-2025080784-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2025-04-17 | — | — | WO | disclosed |