Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17467927 | 0.73 | MEN1 (0.57) | TSHRL3MBTL1MEN1KMT2AHDAC4 | |
| SCHEMBL1107799 | 0.71 | LMNA (0.51) | LMNAF2CES1CES2TSHR | |
| SCHEMBL17467924 | 0.71 | AKR1C1 (0.41) | LMNAAKR1C1MAPTPOLBCYP2C19 | |
| SCHEMBL30046211 | 0.71 | AKR1C1 (0.41) | LMNAAKR1C1MEN1KMT2AHDAC4 | |
| SCHEMBL28433377 | 0.70 | LMNA (0.50) | LMNAF2CES1CES2TSHR | |
| SCHEMBL8396816 | 0.68 | LMNA (0.44) | LMNAF2CES1CES2TSHR | |
| SCHEMBL8765171 | 0.68 | LMNA (0.41) | LMNAF2CES1CES2TSHR | |
| SCHEMBL13562901 | 0.67 | LMNA (0.52) | LMNAF2CES1CES2TSHR | |
| SCHEMBL8766967 | 0.67 | LMNA (0.43) | LMNAF2CES1CES2TSHR | |
| SCHEMBL30936941 | 0.67 | LMNA (0.56) | LMNAF2CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119490397-A | Bicyclo [1.1.0] butanone compound and synthesis method thereof | 浙江工业大学 | 2025-02-21 | — | — | CN | disclosed |