SCHEMBL1107799

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25025696	0.80	HSD11B1 (0.44)	LMNAPNMTHSD11B1ALDH1A1MEN1
	SCHEMBL17467926	0.79	AKR1C1 (0.47)	LMNAPNMTHSD11B1ALDH1A1MEN1
	SCHEMBL30936941	0.78	LMNA (0.56)	LMNAF2ALDH1A1CES2CES1
	SCHEMBL5085323	0.78	AKR1C1 (0.45)	LMNAPNMTHSD11B1ALDH1A1MEN1
	SCHEMBL5081784	0.76	TSHR (0.52)	ALDH1A1CES2CES1TSHRDAO
	SCHEMBL30934615	0.76	OPRM1 (0.42)	LMNAPNMTHSD11B1ALDH1A1TSHR
	SCHEMBL29642400	0.76	PNMT (0.42)	LMNAPNMTHSD11B1ALDH1A1TSHR
	SCHEMBL30555211	0.76	PNMT (0.52)	PNMTMEN1KMT2A
	SCHEMBL3973946	0.76	PNMT (0.52)	PNMTMEN1KMT2A
	SCHEMBL30422688	0.76	KMO (0.48)	ALDH1A1CES2CES1TSHRDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.