Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.48 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.35 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5256825 | 0.86 | LTA4H (0.46) | TEAD1PDE2AGRM2CCR5HRH3 | |
| SCHEMBL1881035 | 0.83 | HRH3 (0.53) | PDE2AGRM2HRH3TSHRMCHR1 | |
| SCHEMBL110617 | 0.82 | HRH3 (0.53) | HRH3TSHRMCHR1 | |
| SCHEMBL1873045 | 0.81 | HRH3 (0.55) | PDE2AGRM2HRH3L3MBTL1TSHR | |
| SCHEMBL12367631 | 0.81 | PDE2A (0.42) | TEAD1PDE2AGRM2HRH3 | |
| SCHEMBL12426 | 0.81 | KCNH2 (0.46) | TEAD1HRH3L3MBTL1TSHRJAK2 | |
| SCHEMBL3057319 | 0.79 | TRPV6 (0.46) | TEAD1PDE2AHRH3L3MBTL1DRD4 | |
| SCHEMBL5254916 | 0.79 | CYP1A2 (0.45) | PDE2AGRM2HRH3L3MBTL1MCHR1 | |
| SCHEMBL3065752 | 0.79 | CXCR4 (0.45) | PDE2AGRM2HRH3SIGMAR1 | |
| SCHEMBL10112329 | 0.79 | KDM4E (0.57) | PDE2AGRM2HRH3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025079989-A1 | PYRAZOLO[3,4-B]PYRIDINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사유한양행 | 2025-04-17 | — | — | WO | disclosed |