Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.54 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.54 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GSK3B | P49841 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2384086 | 0.85 | ALDH1A1 (0.49) | GABRA1GABRG2GABRB3GABRA5ALDH1A1 | |
| SCHEMBL5530559 | 0.82 | ALDH1A1 (0.76) | ALDH1A1GSK3BKDM4EMEN1KMT2A | |
| SCHEMBL11372872 | 0.81 | GSK3B (0.57) | ALDH1A1GSK3BMEN1KMT2ACYP2C19 | |
| SCHEMBL31469740 | 0.79 | GABRA1 (0.46) | GABRA1GABRG2GABRB3GABRA5ALDH1A1 | |
| SCHEMBL31469758 | 0.79 | GABRA1 (0.46) | GABRA1GABRG2GABRB3GABRA5ALDH1A1 | |
| SCHEMBL9392477 | 0.75 | ALDH1A1 (0.69) | ALDH1A1GSK3BKDM4ECYP2C19HIF1A | |
| SCHEMBL15154618 | 0.75 | GSK3B (0.59) | ALDH1A1GSK3BKDM4EMEN1KMT2A | |
| SCHEMBL10674186 | 0.73 | EGFR (0.69) | ALDH1A1GSK3BKDM4EMEN1KMT2A | |
| SCHEMBL12254382 | 0.73 | GSK3B (0.60) | GSK3BKDM4EMEN1KMT2AHIF1A | |
| SCHEMBL2384071 | 0.73 | HIF1A (0.69) | GSK3BMEN1KMT2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025030002-A2 | DGK TARGETING COMPOUNDS AND USES THEREOF | ARVINAS OPERATIONS, INC. (US) | 2025-02-06 | — | — | WO | disclosed |